From EyeWiki
Original article contributed by: Michel J. Belliveau, MD
All contributors: Caroline W. (Sham) Vargason, MD, PhD, Cat Nguyen Burkat, MD FACS, Marcus M. Marcet, MD FACS, Michel J. Belliveau, MD and Shubhra Goel, MD
Assigned editor: Cat.N.Burkat,
Review: Assigned status Up to Date by Cat Nguyen Burkat, MD FACS on September 3, 2015.
{| cellspacing="5"

|-!align="right" |Lead Editors: |add |- !align="right" |Contributing Editors: |add |-


Ectropion is an outward turning of the eyelid margin. Patients may experience symptoms due to ocular exposure and inadequate lubrication. Definitive management is surgical. Medical management is temporizing but can improve symptoms while waiting for surgery.

Ectropion. A patient with involutional ectropion of the left lower eyelid. Keratinization of the palpebral conjunctiva is present. Image courtesy of Marcus M. Marcet, MD FACS.

Disease Entity[edit | edit source]

ICD-9 374.10 Ectropion, unspecified
ICD-10 H02.109 Unspecified ectropion of unspecified eye, unspecified eyelid

Disease[edit | edit source]

Ectropion is an outward turning of the eyelid margin. It primarily involves the lower lid. Upper eyelid eversion can occur in Floppy Eyelid Syndrome.

Etiology[edit | edit source]

There are three main types of ectropion: involutional, cicatricial and paralytic.

Involutional ectropion is caused by increased horizontal laxity of the lower eyelid.

Cicatricial ectropion is caused by shortening of the anterior lamella, which is comprised of the skin and orbicularis muscle.

Paralytic ectropion is caused by decreased orbicularis muscle tone supporting the lower eyelid.

Additionally, mechanical ectropion can occur when a tumor displaces the lower eyelid margin. Finally, congenital ectropion can occur and is rare.    

Risk Factors[edit | edit source]

  • Age (gravity, loss of elasticity)
  • Eyelid rubbing
  • Repeated eyelid pulling (ex. contact-lens use)
  • Floppy eyelid syndrome
  • Long term use of eye drops
  • Skin conditions which involve the eyelid
  • Trauma
  • Prior Eyelid Surgery

General Pathology[edit | edit source]

Ectropion can be classified as:

  • Involutional (most common)
  • Paralytic
  • Cicatricial
  • Mechanical
  • Congenital (very rare)

Pathophysiology[edit | edit source]

In involutional ectropion, the tarsoligamentous sling supporting the eyelid by attachment to the orbital rim via the medial and lateral canthal tendons becomes lax. In paralytic ectropion, orbicularis muscle tone is weak or absent due to facial nerve palsy. In cicatricial ectropion, the anterior or middle lamellae are shortened due to scarring. Midfacial hypoplasia, where the inferior obital rim is located relatively posterior to the eyeball, results in both decreased lower eyelid support and increased propensity for lower eyelid retraction.

Clinical examination[edit | edit source]

Examination reveals outward turning of the eyelid margin.

History[edit | edit source]

In addition to abnormal position of the lid, patients experience tearing, irritation/grittiness/foreign body sensation, red eye, and mucoid discharge. Symptoms are caused by ocular exposure ,inadequate closure and lubrication. Inquire about habitual eye rubbing, which may accompany symptoms of itch from ocular allergy or ocular surface disease.

Physical examination[edit | edit source]

  • Facial architecture:
    Examine the bony architecture of the lower orbital rim and midface position. Patients with hypoplastic midface, also known as hemiproptosis, will have an inferior orbital rim located posteriorly relative to the globe.
  • Facial nerve palsy:
    Inspect the face and test facial muscle strength to assess for paralysis.
  • Eyelid laxity:
    To test for horizontal laxity, place a thumb beneath the lateral canthus and push the eyelid laterally and superiorly. If the lid margin does not roll back into position, suspect a cicatricial component. In involutional cases, the ectropion typically disappears with this maneuver. The eyelid distraction test is done by pulling the lid away from the globe. Normal lid distraction is between 2-3 mm. If it is more than 5mm, there is substantial laxity. In cases of cicatricial ectropion, the eyelid malposition will often become accentuated by asking the patient to look upwards and to open his or her mouth at the same time; the maneuver places the anterior lamella on maximum stretch.
  • Eyelid pathology:
    Examine the eyelid margin under magnification to look for signs of chronic blepharitis, palpebral conjunctival hypertrophy and keratinization, conjunctival scarring, and to rule out suspicious changes such as loss of lashes (madarosis), ulceration, or infiltration.
  • Punctal ectropion:
    Assess the position of the lower punctum which may rotate away with medial laxity and no longer make contact with the ocular surface and tear lake.
  • Ocular surface:
    Examine the cornea for epithelial changes secondary to exposure. 

Differential diagnosis[edit | edit source]

  • Eyelid malignancy
  • Eyelid retraction secondary to proptosis (e.g. thyroid eye disease), excessive tissue removal with lower blepharoplasty, or inferior rectus recession without disinsertion of the lower lid retractors.

Management[edit | edit source]

Definitive management is surgical. Medical management is temporizing but can improve symptoms while awaiting surgery.

Deferral of surgery should be considered in 2 groups of patients. Ectropion induced by long term use of eye drops such as dorzolamide and brimonidine may resolve with discontinuation, if feasible. Patients suffering from inflammatory skin conditions involving the eyelid may have improvement or reversal of ectropion with improved control of inflammation. 

Medical therapy[edit | edit source]

  • Lubrication of the ocular surface
  • Horizontal taping of the eyelid

Surgery[edit | edit source]

  • Lower eyelid laxity: the lower eyelid is horizontally tightening by a lateral tarsal strip or similar procedure.
  • Lower eyelid retractor disinsertion: the Jones procedure of reattaches retractors to the tarsus.
  • Punctual ectropion: the medial spindle procedure reapposes the everted punctum.
  • Cicatricial ectropion often requires lengthening of the anterior lamella by a skin graft.
  • Paralytic ectropion requires horizontal tightening and correction of punctal ectropion. With facial nerve paralysis, corneal exposure and brow ptosis may also need to be addressed.

Complications[edit | edit source]

Ectropion surgery is considered safe and effective. Recurrence does occur occasionally after several years requiring a repeat surgery.

Like any eyelid surgery there is always a possibility of local post-operative bleeding or infection but these are generally minor. Injury to the cornea is possible but uncommon with careful technique.

Additional Resources[edit | edit source]

ASOPRS Information on Ectropion

References[edit | edit source]

  1. Orbit, Eyelids, and Lacrimal System, Section 7. Basic and Clinical Science Course. San Francisco: American Academy of Ophthalmology; 2009.
  2. American Academy of Ophthalmology Focal Points: Ectropion and Entropion, Volume 12, Number 10, 1994.
  3. Hegde V, Robinson R, Dean F, et al. Drug-induced ectropion: what is best practice? Ophthalmology 2007;114:362-366.
  4. Durairaj VD, Horsley MB. Resolution of pityriasis rubra pilaris-induced cicatricial ectropion with systemic low-dose methotrexate. Am J Ophthalmol 2007;143:709-710.
  5. Nerad JA. Techniques in Ophthalmic Plastic Surgery: A Personal Tutorial. Philadelphia: Saunders, 2010. Print.