File:Screenshot 2025-12-21 at 7.41.37 PM.png

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The mechanism of action for omalizumab. Adapted from Pelaia, Girolamo et al. Omalizumab binds to free immunoglobulin E (IgE) so that it hinders binding to IgE receptors (FcεRI). Another alternative mechanism of omalizumab is that this medication can decrease effective IgE receptors shown on the mast cell/Basophil. These two mechanisms both downregulate mast cells and basophils, resulting in decreased swelling. Credit: Clinical photographs taken by Rona Z Silkiss, MD, FACS.

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current19:45, December 21, 2025Thumbnail for version as of 19:45, December 21, 20252,194 × 1,220 (1.25 MB)Rona.Z.Silkiss (talk | contribs)

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