Transient Smartphone Blindness

From EyeWiki
Assigned editor:
Assigned status Up to Date
 by Neelakshi Bhagat, MD, FACS on July 21, 2023.

Transient Smartphone "Blindness" (TSB) is a recent phenomenon characterized by acute, painless, transient vision loss associated with smartphone usage while lying down in the dark [1]. While it is usually monocular, it can rarely present bilaterally [2]. TSB is hypothesized to be a normal physiologic adaptation to differential retinal light sensitivity between the two eyes. Since it can mimic more serious and well-established pathologies, thorough history-taking could differentiate TSB-related transient vision loss from ischemic retinal and optic nerve disorders.


In 2016, Alim-Marvasti et al. described two cases of several months of painless, unilateral, transient vision loss in young individuals (22 and 40 years old) without a reported history of vasculopathic disease. Visual acuity, pupils, intraocular pressures (IOP), color vision by Ishihara plates, fundoscopy, slit lamp examination, optical coherence tomography (OCT), Humphrey Visual Fields (HVF), Magnetic resonance imaging (MRI), and Vitamin A level were all normal. The ocular symptoms occurred in the dark immediately after turning off a smartphone screen - and specifically in a recumbent position with the lower eye occluded. In both cases, the affected eye was contralateral to the side on which the patient was lying and resolved within minutes. [1]

Since then, others have reported the phenomenon of TSB in individuals with similar history and negative workup. [2][3][4][5][6]


The typical history of TSB includes acute, painless, monocular, transient vision loss in the setting of lateral recumbent smartphone usage with low level of ambient light, in which the lower eye is occluded (e.g. by a pillow) and the fellow eye is exposed to the bright screen of the device [1] [4].

Occasionally, subjects have been reported to only see vague outlines of objects in the affected eye with normal vision in the fellow eye [1].

While most frequently reported as monocular, Rondeau et al. have reported a case of a 68-year-old woman who experienced binocular TSB in the context of discovering that the patient's phone was set at its maximum brightness setting [2].


TSB is believed to be due to temporary discrepancy in bleaching of photopigment and ultimate light adaptation between the fellow retinae. The prevailing hypothesis is that in low ambient light, if the individual lies in a position where one eye is functionally blocked (such as with a pillow, bed sheets) the blocked eye becomes dark-adapted while the other eye exposed to the bright screen of the device becomes light-adapted. After the screen of the device is deactivated and the individual reverts to binocular vision in low ambient light, the dark-adapted eye sees well instantly, but the retina of the light-adapted eye - being somewhat bleached - takes a while to adapt and thus perceives temporary blindness. This phenomenon results from differential bleaching of photopigment of the two retinas and can last for a few seconds to several minutes before returning to baseline. [1] [4]

This “bleaching” effect may be a result of transient depletion of 11-cis-ret­inal which cannot recycle quick enough. Alime et al. sought to reproduce these findings with objective electroretinogram (ERG) recording, exposing the authors to a smartphone screen in a low-ambient light room while one eye was occluded. Exposure was at arm's length and re-demonstrated reduced visual sensitivity in the light-exposed eye after screen was powered off with recovery in several minutes. Specifically, the ERG showed reduced B-wave amplitude in the light-exposed eye. [1]

Examination and Diagnostic Procedures

Visual acuity (VA), pupils (i.e. RAPD evaluation), intraocular pressure (IOP), confrontational fields (CFs), extraocular movements (EOMs), and color vision should be evaluated. These parameters would be expected to be normal (i.e. near-normal VA, no RAPD, full CFs, intact and painless EOMs, no color desaturation).

HVF, OCT retina, MRI would all expected to be normal or at least inconsistent with the patient's symptoms.

Differential Diagnosis

TSB must be distinguished from other causes of acute, painless, transient vision loss, especially thromboembolic disease (e.g. amaurosis fugax).

While non-arteritic anterior ischemic optic neuropathy (NAION) may cause acute, painless, unilateral vision loss, symptoms would be expected to persist (i.e. not transient). [7]

Additionally, multiple sclerosis (MS) merits consideration in these patients, although pain with eye movement, color desaturation, and abnormal MRI findings (e.g. periventricular white matter changes, enhancing lesions separated by time and space consistent with demyelinating disease) would be expected [8].

Management and Prognosis

It has been suggested that patients should only use smartphones in well-lit rooms and to assure that neither eye is occluded [9][10]. Patients should additionally be advised against smartphone usage in dark settings (e.g. before bedtime or early morning before dawn) in order to prevent recurrence [9].

Given the transient etiology of this phenomenon, the prognosis has thus far been uniformly promising, with full resolution of symptoms.

Comment Regarding Phone Manufacturers

Recently, mobile phone manufacturers have introduced technology to reduce blue light at certain individuals, such as at night. Hasan et al. have suggested that these manufacturers spread awareness in order to warn their clientele of the side effects of smart phone use in poorly-lit rooms [9].

Clinical Relevance

Correct diagnosis of TSB is imperative as incorrect diagnosis may put patients at risk. If misdiagnosed as thromboembolic etiology (e.g. amaurosis fugax), patients may be unnecessarily started on anticoagulation (such as aspirin [1]) which can pose obvious bleeding risk to the patient. If incorrectly treated as MS, the patient may inappropriately be started on disease-modifying therapies (e.g. interferons, monoclonal antibodies), which pose significant side effects as well as expense. In addition to the field of Ophthalmology, recognition of this entity is relevant to other physicians to which patients with these symptoms present (e.g. Family Medicine, Internal Medicine, Emergency Medicine).

Ultimately, this phenomenon emphasizes the importance of thorough history-taking in ophthalmology and the field of medicine to avoid any unnecessary interventions or investigations.


  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Alim-Marvasti A, Bi W, Mahroo OA, Barbur JL, Plant GT. Transient Smartphone "Blindness". N Engl J Med. 2016 Jun 23;374(25):2502-4. doi: 10.1056/NEJMc1514294. PMID: 27332920.
  2. 2.0 2.1 2.2 Rondeau MW, Sagi A, Voetsch B. Transient smartphone blindness: An unusual case of vision loss in the 21st century. Neurology. 2019; 92(15 supplement). P5. 3-068.
  3. Irshad F, Adhiyaman V. Transient smartphone blindness. Can J Ophthalmol. 2017 Jun;52(3):e107-e108. doi: 10.1016/j.jcjo.2016.10.017. Epub 2017 Jan 18. PMID: 28576218.
  4. 4.0 4.1 4.2 Sathiamoorthi S, Wingerchuk DM. Transient smartphone blindness: Relevance to misdiagnosis in neurologic practice. Neurology. 2017 Feb 21;88(8):809-810. doi: 10.1212/WNL.0000000000003639. Epub 2017 Jan 18. PMID: 28100724.
  5. Eriksen E, Jørstad ØK. Transient smartphone blindness. Tidsskrift for den Norske Laegeforening : Tidsskrift for Praktisk Medicin, ny Raekke. 2021 Mar;141(5). DOI: 10.4045/tidsskr.20.0972. PMID: 33754676.
  6. Robles-Amor P, Miranda-Sánchez, Perales-Casado N, Santos-Bueso E. Transient smartphone-induced blindness. Journal Français d’Ophtalmologie. 2022;45(10):e455—e456. DOI: //
  7. Kerr NM, Chew SS, Danesh-Meyer HV. Non-arteritic anterior ischaemic optic neuropathy: a review and update. J Clin Neurosci. 2009 Aug;16(8):994-1000. doi: 10.1016/j.jocn.2009.04.002. PMID: 19596112.
  8. Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, Correale J, Fazekas F, Filippi M, Freedman MS, Fujihara K, Galetta SL, Hartung HP, Kappos L, Lublin FD, Marrie RA, Miller AE, Miller DH, Montalban X, Mowry EM, Sorensen PS, Tintoré M, Traboulsee AL, Trojano M, Uitdehaag BMJ, Vukusic S, Waubant E, Weinshenker BG, Reingold SC, Cohen JA. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018 Feb;17(2):162-173. doi: 10.1016/S1474-4422(17)30470-2. Epub 2017 Dec 21. PMID: 29275977.
  9. 9.0 9.1 9.2 Hasan CA, Hasan F, Mahmood Shah SM. Transient Smartphone Blindness: Precaution Needed. Cureus. 2017;9(10):e1796. Published 2017 Oct 24. doi:10.7759/cureus.1796
  10. Rod NH, Dissing AS, Clark A, Gerds TA, Lund R. Overnight smartphone use: A new public health challenge? A novel study design based on high-resolution smartphone data. PLoS One. 2018;13(10):e0204811. Published 2018 Oct 16. doi:10.1371/journal.pone.0204811
The Academy uses cookies to analyze performance and provide relevant personalized content to users of our website.